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    <ns5:termsAndConditions xml:lang="ja">条件を付加しない。</ns5:termsAndConditions>
    <ns5:addinfo>&lt;a href='https://brc.riken.jp/mus/pcr10267'&gt;Genotyping protocol -PCR-&lt;/a&gt;</ns5:addinfo>
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    <ns5:termsAndConditions xml:lang="en">No specific terms and conditions.    (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)</ns5:termsAndConditions>
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    <dc:description xml:lang="en">A mutant mouse in which a construct containing a loxP site, FRT site, neo cassette, STOP, FRT site, tetracycline operator (tetO) and loxP site was inserted upstream of the translation initiation site. Homozygous mutants show vacuolation in the white matter at 12 months of age.</dc:description>
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    <ns1:strainDevelopment xml:lang="en">Developed and deposited by Kazuhiro Ikenaka, National Institute of Physiological Sciences, and Kenji Tanaka, Keio University. ES cells derived from 129S6/B6 hybrid were used. Mixed genetic background.</ns1:strainDevelopment>
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    <ns1:donorDNA>phage P1 loxP sites, yeast FRT (flippase recombination target) sites, mouse PGK promoter,  E. coli EM7 promoter, E. coli Neomycin resistance gene, yeast  His3 3' UTR, SV40 polyA signal, E. coli Tetracycline operator site, CMV minimal promoter, mouse Mlc1 genomic DNA</ns1:donorDNA>
    <dc:description xml:lang="ja">アストロサイト特異的に発現する遺伝子、Mlc1の翻訳開始部位の直前にNeoSTOPtetOがノックインしてある。Homozygoteはノックアウトマウスになる。</dc:description>
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    <ns5:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns5:addinfo>
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